1689-1697: King William's War (American counterpart of the War of the Grand Alliance in Europe) -- Abenakis, Penobscot, other New England tribes, attacked by English and their Iroquois allies. This is the first of the French-English wars for control of North America, continuing to 1763. During these wars, the Iroquois League generally sides with the English, and the Algonquian tribes with the French.
1689: Nicolas Perrot formally claims upper Mississippi region for France.
1689: The Iroquois kill many French settlers at Lachine.