John Robert Stanley Fincham FRS FRSE (11 August 19269 February 2005) was a noted British geneticist who made important contributions to biochemical genetics and microbial genetics. Perhaps most notably, he obtained the first direct evidence for the "one gene-one enzyme" hypothesis. He accomplished this considerable feat using mutants of Neurospora crassa deficient in a specific enzyme.

Fincham was educated at Peterhouse, Cambridge, where he read Natural Sciences. He did his PhD in the Botany School at Cambridge and then did a year's postgraduate research at Cal Tech with Sterling Emerson (whose daughter Ann he married).[1]

Fincham was the Arthur Balfour Professor of Genetics at Cambridge University between 1984 and 1991. He was elected a Fellow of the Royal Society in 1969 and a Fellow of the Royal Society of Edinburgh in 1978.

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